Thursday, January 17, 2008

SAS Programming in the Pharmaceutical Industry

SAS Programming in the Pharmaceutical Industry

At last! A real-world reference guide for clinical trial SAS programming, packed with solutions that programmers can apply to their day-to-day problems. Discover key techniques and tools available within Base SAS (including the macro language and PROC SQL), SAS/GRAPH, and SAS/STAT that can be used to resolve many common issues in working with clinical trial data. Organized to reflect the statistical programmer's work flow, this user-friendly text begins with an introduction to the working environment, then presents chapters on importing and massaging data into analysis data sets, producing clinical trial output, and exporting data. Valuable plug-and-play programming examples are provided throughout. Whether you're a novice seeking an introduction to SAS programming for the pharmaceutical industry or a junior-level programmer exploring new approaches to problem solving, you'll find a wealth of practical suggestions to help you sharpen your skills.

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Computer Applications in Pharmaceutical Research and Development

Computer Applications in Pharmaceutical Research and Development

A unique, holistic approach covering all functions and phases of pharmaceutical research and development

While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process.

Chapters are organized into the following sections:

* Computers in pharmaceutical research and development: a general overview
* Understanding diseases: mining complex systems for knowledge
* Scientific information handling and enhancing productivity
* Computers in drug discovery
* Computers in preclinical development
* Computers in development decision making, economics, and market analysis
* Computers in clinical development
* Future applications and future development

Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent structure and approach throughout the book. Figures are used extensively to illustrate complex concepts and multifaceted processes. References are provided in each chapter to enable readers to continue investigating a particular topic in depth. Finally, tables of software resources are provided in many of the chapters.

This is essential reading for IT professionals and scientists in the pharmaceutical industry as well as researchers involved in informatics and ADMET, drug discovery, and technology development. The book's cross-functional, all-phases approach provides a unique opportunity for a holistic analysis and assessment of computer applications in pharmaceutics.

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HPLC Method Development for Pharmaceuticals, Volume 8

HPLC Method Development for Pharmaceuticals, Volume 8

High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective.

HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge.

* Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory
* Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities)
* Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase

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http://rapidshare.com/files/74149161/HPLC_Method_Develop_Pharma.zip

Validating Pharmaceutical Systems: Good Computer Practice in Life Science Manufacturing

Validating Pharmaceutical Systems: Good Computer Practice in Life Science Manufacturing

This highly readable text offers a pragmatic approach to the validation of automated/computerized systems, an essential core task when establishing and maintaining compliance with global regulatory authorities, such as the FDA and the MHRA. It examines the different levels of automated systems used throughout the drug development, manufacture, and delivery life cycle, using the GAMP-4 life cycle approach to their validation. Rich with case studies and real-life examples, it also supplies the reader with true applications of GAMP 4 to different areas of regulations, such as good laboratory practice, good clinical practice, good manufacturing practice, and good data practice.

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Facility Validation: Theory, Practice, and Tools

Facility Validation: Theory, Practice, and Tools

Focusing on validation issues specific to the start-up of a new or upgraded manufacturing facility, this book provides definitions of the policies, guidelines, and regulations relating to Good Manufacturing Practices (GMPs) in pharmaceutical industries worldwide. The author discusses the validation concepts, definitions, and terminology associated with GMPs and details the philosophy and key principles of validation. He demonstrates how to set up an infrastructure for implementing a validation program. Included in the book are practical examples of validation documents and SOPs, a comprehensive glossary of validation terminology, and coverage of best practices for evaluating validation programs.

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Injectable Dispersed Systems: Formulation, Processing and Performance

Injectable Dispersed Systems: Formulation, Processing and Performance

This authoritative guide will serve as the most current source on the design and manufacturing of parenteral dispersed systems-showcasing the utility of dispersed systems in drug delivery, drug targeting, and pharmaceutical engineering.

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Pharmaceutical Experimental Design

Pharmaceutical Experimental Design

This useful reference describes the statistical planning and design of pharmaceutical experiments, covering all stages in the development process-including preformulation, formulation, process study and optimization, scale-up, and robust process and formulation development. Shows how to overcome pharmaceutical, technological, and economic constraints on experiment design! Directly comparing the advantages and disadvantages of specific techniques, Pharmaceutical Experimental Design · offers broad, detailed, up-to-date descriptions of designs and methods not easily accessible in other books · reviews screening designs for qualitative factors at different levels · presents designs for predictive models and their use in optimization · highlights optimization methods, such as steepest ascent, optimum path, canonical analysis, graphical analysis, and desirability · discusses the Taguchi method for quality assurance and approaches for robust scaling up and process transfer · details nonstandard designs and mixtures · analyzes factorial, D-optimal design, and offline quality assurance techniques · reveals how one experimental design evolves from another · and more! Featuring over 700 references, tables, equations, and drawings, Pharmaceutical Experimental Design is suitable for industrial, research, and clinical pharmaceutical scientists, pharmacists, and pharmacologists; statisticians and biostatisticians; drug regulatory affairs personnel; biotechnologists; formulation, analytical, and synthetic chemists and engineers, quality assurance personnel; all users of statistical experimental design in research and development; and postgraduate and postdoctoral research workers in these disciplines.

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Filing Patents Online: A Professional Guide

Filing Patents Online: A Professional Guide

Securing a patent through the traditional paper process is slow and expensive. Market demands and the worldwide migration to online patent application systems require attorneys and inventors alike to become familiar with Wweb-based filing. Pursuing patents via the Internet is quicker and more affordable, and makes good business sense. Unfortunately, existing online patent software is cumbersome and difficult to master, forcing many inventors and attorneys to rely on outdated, expensive methods. Filing Patents Online: A Professional Guide provides patent attorneys, inventors, and businesses with a step-by-step guide for filing and pursuing patents electronically. This comprehensive analysis of online patent systems from around the world recommends the proper choices for filers, saving time and money and increasing the odds of success. By following the hands-on examples of real filings contained in this book and its accompanying media kit, you can harness the power of the Internet to research, plan, and write winning claims. Filing Patents Online can result in thousands of dollars in savings and a secured patent that will keep a company ahead of the competition.

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International Pharmaceutical Registration

International Pharmaceutical Registration

The increasing globalization of pharmaceutical markets and continuing consolidation within the pharmaceutical industry have highlighted the challenges of rapidly evolving regulatory requirements and created a much greater appreciation of the need for regulatory awareness throughout the industry. This book provides a practical overview and guide to the complexities of international pharmaceutical registration. With individual country chapters written by experts within that country drawn from regulatory authorities, international pharmaceutical companies, and regulatory consultants, the book comprehensively covers regulations across the globe.

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What is Packaging Design? (Essential Design Handbook)

What is Packaging Design? (Essential Design Handbook)

Book Description:

"A thoughtful and thorough book with some inspiring work -- great for students and anyone taking their first steps into the world of packaging."

This is a highly visual, compact-format sourcebook, packed with top international packaging designers' contemporary work, accompanied by essays on the surrounding issues.

What Is Packaging Design? lays the foundations and professional guidelines for best practice when designing contemporary packaging. It opens with several short essays which define good packaging design and the issues faced by designers in this field. Design basics such as format, layout and typography are explored within the context of packaging design, taking into account genre-specific elements such as product information, branding, marketing and legislation.

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Coatings Technology: Fundamentals, Testing, and Processing Techniques

Coatings Technology: Fundamentals, Testing, and Processing Techniques

Drawn from the third edition of The Coatings Technology Handbook, this book focuses entirely on testing, experimental design, and strategies for selecting processing techniques in the coatings, adhesives, paints, and inks industries. Coatings Technology: Fundamentals, Testing, and Processing Techniques contains the latest coating and processing methods capable of satisfying increasingly precise, application-specific requirements. The book contains analytical techniques used to elucidate surface chemistry, adhesion, and other physical properties. It also presents practical methods, such as accelerated light stability tests, to compare the resistance of different materials to wear, UV light/fading, and weathering. Subsequent chapters explore the most suitable techniques and the equipment for applying materials to different substrates, depending on material properties, service needs, and substrate types. Considering metal and nonmetal coatings and substrates, the book highlights the most recent advances on ink-jet printing, electrodeposition, vapor/chemical deposition technologies, high-speed dispersion, and other cutting-edge methods. Coatings Technology: Fundamentals, Testing, and Processing Techniques provides the the necessary information for scientists and engineers to perform testing and determine what materials and processing technique is most suitable for their own applications.

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Remington: The Science and Practice of Pharmacy

Remington: The Science and Practice of Pharmacy (Remington the Science and Practice of Pharmacy)


For over 100 years, Remington has been the definitive textbook and reference on the science and practice of pharmacy. This Twenty-First Edition keeps pace with recent changes in the pharmacy curriculum and professional pharmacy practice. More than 95 new contributors and 5 new section editors provide fresh perspectives on the field. New chapters include pharmacogenomics, application of ethical principles to practice dilemmas, technology and automation, professional communication, medication errors, re-engineering pharmacy practice, management of special risk medicines, specialization in pharmacy practice, disease state management, emergency patient care, and wound care. Purchasers of this textbook are entitled to a new, fully indexed Bonus CD-ROM, affording instant access to the full content of Remington in a convenient and portable format.

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Part - I: http://rapidshare.com/files/45552201/Remington.part1.rar

Part - II: http://rapidshare.com/files/45685773/Remington.part2.rar

Cosmetics Additives: An Industrial Guide

Cosmetics Additives: An Industrial Guide

Describes about 4000 cosmetics additives currently available for industrial use, compiled from information from 84 manufacturers and distributors. The cosmetics and personal care products industry has a $60 billion market worldwide, and future growth is expected. In the US the market breaks down roughly into: hair care-20%, fragrances-20%, skin care-14%, makeup-17%, deodorants and skin and body lotions-10%, and oral care products-10%. Growth is expected in products targeting ethnic markets and working women. The book lists the following product information, as available, in the manufacturer’s own words: (1) Company name and product category, (2) Trade name and product number, (3) Product description. Also included are a Trade Name Index and a list of Suppliers’ Addresses.

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Thin Layer Chromatography : A Modern Practical Approach

Thin Layer Chromatography : A Modern Practical Approach (Rsc Chromatography Monographs)

Thin-Layer Chromatography (TLC) is a modern, reliable tool that complements other chromatographic techniques. This book provides a practical guide to the basic principles, procedures, and pitfalls on the practical application of TLC.

Thin Layer Chromatography: A Modern Practical Approach offers a sequence of chapters following the steps of the technique as the chromatographer would follow them. The chapters provide a choice of sorbent best suited to the separation intended, followed by pre-treatment required for the sample, applying the sample to the sorbent layer, development procedure, visualisation and detection, and finally quantification. Imaging and hyphenation techniques are described. The reasons why recommendations are made for specific and more general methods are covered. The book also provides an overview of some recent developments in the field.

This practical guide is an invaluable introduction to Thin-Layer Chromatography, and will be welcomed by undergraduate students and the practising chromatographer in industry and academia.

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Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems

Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems

To facilitate the development of novel drug delivery systems and biotechnology-oriented drugs, the need for new, yet to be developed, and approved excipients continues to increase. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems serves as a comprehensive source to improve understanding of excipients and forge potential new avenues for regulatory approval. This book presents detailed, up-to-date information on various aspects of excipient development, testing, and technological considerations for their use. It addresses specific details such as historical perspective, preclinical testing, safety, and toxicology evaluation, as well as regulatory, quality, and utility aspects. The text also describes best practices for use of various functional excipients and extensive literature references for all topics.

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Modern Pharmaceutics

Modern Pharmaceutics

Completely revised and expanded throughout. Presents a comprehensive integrated, sequenced approach to drug dosage formulation, design, and evaluation. Indentifies the pharmacodynamic and physicochemical factors influencing drug action through various routes of administration.

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http://rapidshare.com/files/63596960/Modern_Pharmaceutics.zip

Design of Controlled Release Drug Delivery Systems

Design of Controlled Release Drug Delivery Systems

Enhancement in Drug Delivery offers an accessible compendium covering a wide spectrum of methods to enhance drug delivery and absorption by various routes of administration. Drawing from a number of disciplines, it gives students and practitioners in pharmaceutics, medicine, and health-related disciplines a much-needed guide to current practices. It also provides a starting place for those working on delivery systems for new drugs or seeking to improve current systems by drawing on means applied in other routes. Organized by routes of delivery, the book covers oral, rectal, buccal and sublingual, dermal and transdermal, ocular, vaginal and uterine, nasal and brain administrations.

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Design of Controlled Release Drug Delivery Systems

Design of Controlled Release Drug Delivery Systems

The goal of every drug delivery system is to deliver the precise amount of a drug at a pre-programmed rate to the desired location in order to achieve the drug level necessary for the treatment. An essential guide for biomedical engineers and pharmaceutical designers, this resource combines physicochemical principles with physiological processes to facilitate the design of systems that will deliver medication at the time and place it is most needed.

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http://rapidshare.com/files/75545550/Design_Contro_Release_DDS.zip

Pharmaceutical Process Engineering

Pharmaceutical Process Engineering

Summarizing fundamental engineering principles and operations critical to converting bulk pharmaceutical products into patient-ready and appropriate drug delivery dosage forms, Pharmaceutical Process Engineering facilitates comprehensive understanding of the practical aspects of drug production in an accessible, step-by-step format. It provides a pharmaceutical perspective on unit operations that improves communication among diverse professionals in the field-from pharmaceutical researchers to chemical and industrial engineers-and fully covers the relationship of pharmaceutical development to the application of key concepts and major unit operations in pharmaceutical engineering.

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http://rapidshare.com/files/75786689/Pharma_Process_Eng.zip

Transdermal Drug Delivery, Second Edition

Transdermal Drug Delivery, Second Edition

Completely revised, the Second Edition of Transdermal Drug Delivery presents discussions of the key issues pertinent to transdermal drug delivery. Covering the depth and breadth of the field, from physical chemistry and assessment of drug permeability to available enhancement technologies, to regulatory approval, the book examines topics necessary to the critical evaluation of a drug candidate's potential for delivery across the skin. It describes how to determine the transdermal permeability of drugs, how rationally to select candidates for transdermal delivery, how to choose chemical and/or physical methods to enhance skin transport, and how to solve regulatory issues.

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http://rapidshare.com/files/75978219/Transd_Drug_Delivery_2Ed.zip

Active Pharmaceutical Ingredients: Development, Manufacturing, and Regulation

Active Pharmaceutical Ingredients: Development, Manufacturing, and Regulation

Focusing on the three most critical components that successfully bring an API to market-process development, manufacturing, and governmental regulation and approval-this reference serves as a step-by-step guide to the planning and clear understanding of the bulk manufacturing of APIs. It offers current and timely discussions of the process development cycle, design engineering, the approval process, quality control and assurance, and validation, as well as plant manufacturing activities including materials management, maintenance, and safety. Filling a gap in the literature, this guide covers all the essential information required to effectively plan and execute manufacturing APIs.

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http://rapidshare.com/files/81903714/api_dmr.zip

Advanced Drug Formulation Design to Optimize Therapeutic Outcomes

Advanced Drug Formulation Design to Optimize Therapeutic Outcomes

This title demonstrates how advanced formulation designs and delivery technologies can be used to improve drug efficacy and treatment outcomes in particular therapeutic categories or disease states. It discusses nanoparticle systems for cancer treatments, and also presents cutting edge immono-regulation agents for transplantation and the local targeting of drugs, especially poorly water soluble drugs to provide enhanced therapeutic outcomes. In addition, this title highlights areas of therapy showing the most promise for improvement in clinical outcomes via advanced formulation design.

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http://rapidshare.com/files/81884254/Adv_Drug_Formu_Design.zip

Active Pharmaceutical Ingredients: Development, Manufacturing, and Regulation

Active Pharmaceutical Ingredients: Development, Manufacturing, and Regulation

Focusing on the three most critical components that successfully bring an API to market-process development, manufacturing, and governmental regulation and approval-this reference serves as a step-by-step guide to the planning and clear understanding of the bulk manufacturing of APIs. It offers current and timely discussions of the process development cycle, design engineering, the approval process, quality control and assurance, and validation, as well as plant manufacturing activities including materials management, maintenance, and safety. Filling a gap in the literature, this guide covers all the essential information required to effectively plan and execute manufacturing APIs.

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http://rapidshare.com/files/81903714/api_dmr.zip

Pharmaceutical Dosage Forms: Disperse Systems, Volume 3

Pharmaceutical Dosage Forms: Disperse Systems, Volume 3

This third volume of the second edition offers information on specialized products such as emulsions, liposomes, polymers and polymeric pharmaceutical excipients. It explains the requirements for conducting clinical research and obtaining marketing approval for new drug products.

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http://rapidshare.com/files/82618031/Pharma_DF_ds3.zip

Good Manufacturing Practices and Inspection (Quality Assurance of Pharmaceuticals)

Good Manufacturing Practices and Inspection (Quality Assurance of Pharmaceuticals)

Quality assurance of pharmaceutical products is a continuing concern of WHO. Despite efforts made around the world to ensure a supply of quality and effective medicines, substandard, spurious and counterfeit products still compromise health care delivery in many countries. To respond to the global need for adequate quality assurance of pharmaceuticals, WHO's Expert Committee on Specifications for Pharmaceutical Preparations has over the years made numerous recommendations to establish standards and guidelines and to promote the effective functioning of national regulatory and control systems and the implementation of internationally agreed standards by trained personnel. Many of the relevant documents endorsed by the Committee are reproduced in this volume, providing guidance covering all aspects of good manufacturing practices (GMP). Important texts on inspection are also included. Most of the material has been published separately in the Expert Committee's reports. This compendium brings it together to make it more accessible and of greater practical value to those working in faculties of pharmacy, in medicines regulation and control, and in the pharmaceutical industry.

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http://rapidshare.com/files/83128479/GMP_Inspect_QA_Pharma.zip

Fiedler Encyclopedia of Excipients: For Pharmaceuticals, Cosmetics and Related Areas

Fiedler Encyclopedia of Excipients: For Pharmaceuticals, Cosmetics and Related Areas

The two-volume encyclopedia offers a detailed description of properties, analyses and characteristic data for more than 17,000 excipients used in the manufacture of pharmaceuticals, cosmetics and related products. In addition, pharmacological and toxicological properties as well as allergy-inducing reactions are evaluated. Information on manufacturers is given in a directory at the end of the second volume.

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http://rapidshare.com/files/83697345/Fiedleree.part1.rar

http://rapidshare.com/files/83948484/Fiedleree.part2.rar

Columns for Gas Chromatography: Performance and Selection

Columns for Gas Chromatography: Performance and Selection
Columns

Columns for Gas Chromatography: Performance and Selection
Wiley-Interscience | ISBN:0471740438 | Edition - 2007-04-13 | PDF | 298 pages| 13 MB | Rapidshare & Megaupload

Choosing the right column is key in Gas Chromatography

Gas Chromatography (GC) is the most widely used method for separating and analyzing a wide variety of organic compounds and gases. There have been many recent advancements in both packed column and capillary column GC. With numerous options and considerations, selecting the right column can be complicated. This resource provides essential guidance for scientists and technicians, including:

* Methods of choosing both capillary and packed columns
* Selection of dimensions (column length, I.D., film thickness, etc.) and type of column
* Guidelines for proper connections of the column to the injector and detector
* United States Pharmacopeia and National Formulary chromatographic methods
* ASTM, EPA, NIOSH, and OSHA column selection specifications
* Information on the advantages of computer assistance in GC and multidimensional GC
* Comprehensive information on column oven temperature control

Columns for Gas Chromatography: Performance and Selection is a hands-on reference for scientists and technicians using GC.


Quality Assurance in Analytical Chemistry:

Quality Assurance in Analytical Chemistry: Applications in Environmental, Food and Materials Analysis, Biotechnology, and Medi

Quality Assurance in Analytical Chemistry:
Applications in Environmental, Food and Materials Analysis, Biotechnology, and Medi
Publisher: Wiley-VCH | 2007-01-09 | ISBN:3527311149 | Pages:300 | PDF | 2 MB


Book Description:

This best-selling title both in German and English is now enhanced by a new chapter on the important topical subject of measurement uncertainty, plus a CD-ROM with interactive examples in the form of Excel-spreadsheets. These allow readers to gain an even better comprehension of the statistical procedures for quality assurance while also incorporating their own data.

Following an introduction, the text goes on to elucidate the 4-phase model of analytical quality assurance: establishing a new analytical process, preparative quality assurance, routine quality assurance and external analytical quality assurance.

Besides updating the relevant references, the authors took great care to incorporate the latest international standards in the field.

Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.

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MIRROR


Research and Development in the Chemical and Pharmaceutical Industry

Research and Development in the Chemical and Pharmaceutical Industry

Peter Bamfield, "Research and Development in the Chemical and Pharmaceutical Industry"
Wiley-VCH; 3 edition (October 20, 2006) | ISBN: 3527317759 | 289 pages | PDF | 1 Mb

Review
"…a very interesting and well-written book…" (Journal of Hazardous Materials, July 16, 2007)

'The nuts and the bolts of R&D management in the chemical industry in a sound book and a very practical primer' (Chemistry & Industry)

Book Description
Mastering management skills is hard to achieve by newcomers starting their careers in the chemical industry. The message coming from there is that good chemists swiftly have to become good managers if they are to survive and progress in today's competitive climate.

This book is designed to help guide younger R & D chemists to ways in which they can quickly evolve skills which are built around three factors - people, knowledge and time. It covers the management of scientific personnel, management within a variety of R & D organisational structures, creating a climate of innovation, the management of projects including the time management and communication aspects of the job.

The author, Peter Bamfield, is now working as a consultant. Due to his long experience in the chemical industry, he was elected President of the Royal Society of Chemistry's Industrial Affairs Division.

This third edition of the book has been revised and updated to take global developments and recent changes in regulatory affairs into account.

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http://rapidshare.com/files/71785652/Research_and_Development_in_the_Chemical_and_Pharmaceutical_Industry.pdf

HPLC in Enzymatic Analysis

HPLC in Enzymatic Analysis

Edward F. Rossomando, "HPLC in Enzymatic Analysis"
Wiley-Liss; 22 edition (April 7, 1998) | ISBN:0471103403 | 451 pages | PDF | 15,4 Mb


The use of High Performance Liquid Chromatography (HPLC) techniques in the study of enzymatic reactions has grown significantly since the publication of the first edition of this highly successful book: the role of enzymes in biological research has expanded; the application of HPLC and enzymes has extended to more disciplines; advances in separation techniques and instrumentation have increased the capability of HPLC; and the discovery of new enzymes has spawned new methods of analysis.

High Performance Liquid Chromatography in Enzymatic Analysis, Second Edition addresses these developments in its coverage of the refinements of HPLC methods and their use in a wide range of laboratory applications. It offers the same practical approach found in the first edition, incorporates a wealth of new information into existing chapters, and adds new chapters to deal with new applications, including capillary electrophoresis, forensic chemistry, microdialysis, and the polymerase chain reaction. Topics include:
* Application of HPLC to the assay of enzymatic activities
* Concepts and principles of HPLC, including the latest technological advances
* Concepts and principles of capillary electrophoresis (CE)
* Strategy for design of an HPLC/CE system for assay of enzyme activity
* Preparation of enzymatic activities from tissues and single cells
* Analysis of enzymatic activities in body fluids, including chromatobiosis
* HPLC for the identification of new enzymatic activities
* Fundamentals of the polymerase chain reaction
* HPLC in forensics
* Survey of enzymatic activities assayed by the HPLC method, including many new categories
* Multienzyme systems, including many new examples
* HPLC in the analysis of contaminated food

"It is the ability of HPLC to accomplish separations completely and rapidly that led to its original application to problems in the life sciences, particularly those related to purification. An analysis of the literature revealed that this technique was used primarily for the purification of small molecules, macromolecules such as peptides and proteins, and more recently, antibodies. This application to purification has all but dominated the use of the method, and there has been a plethora of books, symposia, and conferences on the use of HPLC for these purposes. However, it was only a matter of time before others began to look beyond and to explore the possibilities that result from the capacity to make separations quickly and efficiently." --from the preface to the First Edition

Easy to read and full of practical advice and hundreds of diagrams and examples, High Performance Liquid Chromatography in Enzymatic Analysis, Second Edition is an invaluable resource for students, researchers, and laboratory workers in analytical chemistry and biochemistry, molecular biology and cell biology, and for anyone interested in keeping up with this fast-growing field.

Gas Chromatography: Analytical Chemistry by Open Learning

Gas Chromatography: Analytical Chemistry by Open Learning

Ian A. Fowlis, "Gas Chromatography: Analytical Chemistry by Open Learning"
Wiley; 22 edition (May 1995) | ISBN: 0471954683 | 278 pages | PDF | 11,9 Mb

Approaches the subject from the perspective of a chromatographer who needs to know enough theory to make the best use of a chosen technique. Emphasizes the actual application of the methods--not just the theories on which they are based. This edition features a number of advances in the field since publication of the first volume. These include new chapters on high resolution gas chromatography (GC), GC detectors and classification of GC. Self-assessment questions ensure full understanding of the concepts.



Medical Biochemistry

Medical Biochemistry


Mosby | ISBN: 0723433410 | 2 edition (December 17, 2004) | CHM | 696 pages | 45.503 MB

The New Edition of this well-regarded textbook combines basic science and clinical medicine in a concise, easy-to-read format. Fully revised and updated, it reflects the latest information on genetic and molecular biology and integrates even more clinical medicine into the text. At the same time, it retains the dynamic, full-color design that made the first edition such a successcomplete with case histories, advanced concept boxes, and color illustrations that clarify complex biochemical concepts. New summary boxes and an expanded self-assessment section make the text even more useful for review and study.

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NMR - From Spectra to Structures

NMR - From Spectra to Structures


Springer; 2nd rev.and exp.ed. edition (September 10, 2007) | ISBN:3540721959 | PDF | 208 pages | 3.5 Mb

Nuclear magnetic resonance spectroscopy is one of the most powerful analytical methods. This practice-oriented textbook aims at teaching how NMR experiments should be used to make structural asssignments. The book is intended as a practical guide for students and laboratory personnel, so that the emphasis is on practical rather than on theoretical aspects, which are treated only to the extent necessary to understand the experiments and to interpret the results.
The second edition has been expanded to include several other heteronuclei (15N, 19F, 29Si, 77Se, 113Cd, 117Sn/119Sn, 195Pt, 207Pb) and a new chapter on solid state NMR. The problems section has been enlarged and now includes 50 problems. These are of different degrees of complexity and in all cases include two-dimensional (2D) methods as well as standard proton and carbon 1D spectra.


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Chemical Analysis: Modern Instrumentation Methods and Techniques Second Edition

Chemical Analysis: Modern Instrumentation Methods and Techniques Second Edition


Wiley; 2 edition (May 25, 2007) | ISBN-10: 0470859032 | PDF | 600 pages | 11.1 Mb


Completely revised and updated, Chemical Analysis: Second Edition is an essential introduction to a wide range of analytical techniques and instruments. Assuming little in the way of prior knowledge, this text carefully guides the reader through the more widely used and important techniques, whilst avoiding excessive technical detail.
Provides a thorough introduction to a wide range of the most important and widely used instrumental techniques
Maintains a careful balance between depth and breadth of coverage
Includes examples, problems and their solutions
Includes coverage of latest developments including supercritical fluid chromatography and capillary electrophoresis



Sample Preparation in Chromatography

Sample Preparation in Chromatography


Elsevier Science | 2002-05-01 | ISBN:0444503943 | 942 pages | PDF | 31,6 Mb


Sample preparation is an essential step in many analyses. This book approaches the topic of sample preparation in chromatography in a methodical way, viewing it as a logical connection between sample collection and analytical chromatography. Providing a guide for choosing the appropriate sample preparation for a given analysis, this book describes various ways to process the sample, explaining the principle, discussing the advantages and disadvantages, describing the applicability to different types of samples, and showing the fitness to specific chromatographic determinations.

The first part of the book contains an overview of sample preparation showing its relation to sample collection and to the core chromatographic analysis. The second part covers procedures that do not use chemical modifications of the analyte and includes methods for sample dissolution, concentration and cleanup designed mainly for modifying the initial matrix of the sample. This part starts with conventional separations such as filtration and distillation and finishes with more advanced techniques such as solid phase extraction and electroseparations. The third part gives a description of the chemical modifications that can be performed on a sample either for fractionation purposes or to improve a specific property of the analyte. This part includes derivatizations, polymer chemical degradations, and pyrolysis.


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HPLC: A Practical Guide

HPLC: A Practical Guide


Royal Society of Chemistry; 1 edition (October 20, 2004) | ISBN: 0854045155 | 150 pages | PDF | 8,1 Mb

Provides the answers to two basic questions often asked by students of chromatography: how these compounds can be separated and why the method was used, enabling the reader to grasp the concepts of the technique using simple, representative chromatograms.

Chemometrics in Spectroscopy

Chemometrics in Spectroscopy


Academic Press | ISBN: 012374024X | July 24, 2007 | PDF | 800 pages | 23.7 MB

Chemometrics in Spectroscopy builds upon the statistical information covered in other books written by these leading authors in the field by providing a broader range of mathematics and progressing into the fundamentals of multivariate and experimental data analysis. Subjects covered in this work include: matrix algebra, analytic geometry, experimental design, calibration regression, linearity, design of collaborative laboratory studies, comparing analytical methods, noise analysis, use of derivatives, analytical accuracy, analysis of variance, and much more are all part of this chemometrics compendium. Developed in the form of a tutorial offering a basic hands-on approach to chemometric and statistical analysis for analytical scientists, experimentalists, and spectroscopists. Without using complicated mathematics, Chemometrics in Spectroscopy demonstrates the basic principles underlying the use of common experimental, chemometric, and statistical tools. Emphasis has been given to problem-solving applications and the proper use and interpretation of data used for scientific research.

* Offers basic hands-on approach to chemometric and statistical analysis for analytical scientists, experimentalists, and spectroscopists.
* Useful for analysts in their daily problem solving, as well as detailed insights into subjects often considered difficult to thoroughly grasp by non-specialists.
* Provides mathematical proofs and derivations for the student or rigorously-minded specialist


Introduction to Medicinal Chemistry: How Drugs Act and Why

Introduction to Medicinal Chemistry: How Drugs Act and Why


Wiley-VCH; 1 edition | ISBN-10: 0471185450 | 736 Pages | Djvu | 22,3 Mb

This work brigdges the compartmentalized undergraduate organic and biochemistry and biology subjects to the pharmacology and the clinical areas a modern pharmacy practice requires. The changes and constantly increasing responsibilities of today's pharmacist have dictated a restructuring of the pharmacy curriculum, including individual course content. This book reflects and addresses these developments. This is a well-written work that covers most major areas of pharmaceutical research. The text is presented in a logical and concise fashion being divided into chapters based upon therapeutic topic. This makes the work very useful for teaching a course in medicinal chemistry since therapeutic areas can be separately covered without having to make use of the entire book which overall contains a tremendous amount of information. This book is a significant contribution to understanding what medicinal chemistry is and how this science is used to develop new therapeutic agents.


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part2 http://depositfiles.com/files/2823824

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An Introduction to Medicinal Chemistry

An Introduction to Medicinal Chemistry


Oxford University Press, USA; | ISBN-10: 0199275009 | 768 pages | PDF | 10,4 Mb

Review: `Review from previous edition "There is excellent all-round coverage here for both undergraduates and postgraduate researchers ... This is a textbook which should be used throughout all medicinal chemistry courses."' Chemistry and Industry 2002

`"In summary Patrick is in my opinion the best text support for a Medicinal Chemistry programme and it continues to be better and better with each review..."' Stuart Warriner, University of Leeds, 2004

Book Description
Many of us think nothing of taking a painkiller to ease a headache, or to relieve the symptoms of 'flu. But how do drugs have their effect in the human body? How are new drugs discovered and designed to be as effective as possible? An Introduction to Medicinal Chemistry offers an engaging insight into the one field of chemistry that arguably has the greatest impact on our quality of life than any other. Newly structured into four parts, the book opens in Part A with an introduction to pharmacodynamics and pharmacokinetics. Pharmacodynamics considers the types of molecular targets used by drugs, the interactions which are involved when a drug meets that target, and the consequences of those interactions. Pharmacokinetics considers the issues involved in a drug reaching its target in the first place. Part B goes on to examine the general principles and strategies involved in discovering and designing new drugs and developing them for the marketplace, while Part C looks at particular 'tools of the trade' which are invaluable in those processes. Finally, Part D covers a selection of specific topics within medicinal chemistry. Reflecting a change in emphasis in medicinal chemistry research, this Part takes us from the largely trial-and-error approach to drug design to the rational approach, and explores the most recent advances in molecular biology and genetics which have revolutionised drug design. With a striking new two-colour text design, and greatly enriched learning features, the third edition conveys the fascination of working in a field which overlaps the disciplines of chemistry, biochemistry, physiology, microbiology, cell biology, and pharmacology. A must-have textbook for any student of medicinal chemistry. Online Resource Centre - Figures available to download, to facilitate lecture preparation - 3D molecular structures, to enable students to visualise key structures in an interactive way - Multiple choice questions with answers, to support and encourage independent learning

Vogel's Textbook of Practical Organic Chemistry (5th Edition)

Vogel's Textbook of Practical Organic Chemistry (5th Edition)


Prentice Hall | ISBN: 0582462363 | 1996 | HTML & PDF | 1552 Pages | 13.2 Mb

Most widely used, established and respected reference manual for the organic chemistry laboratory. Incorporates new reactions and techniques now available to the organic chemist.



Pas is: gigapedia.org

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Advanced Organic Chemistry, Fourth Edition - Part B: Reaction and Synthesis

Advanced Organic Chemistry, Fourth Edition - Part B: Reaction and Synthesis


Springer; 4th ed. edition (June 30, 2001) | ISBN:0306462443 | 958 pages | PDF | 7,8 Mb


The control of reactivity to achieve specific syntheses is one of the overarching goals of organic chemistry. In the decade since the publication of the third edition, major advances have been made in the development of efficient new methods, particularly catalytic processes, and in means for control of reaction stereochemistry. This volume assumes a level of familiarity with structural and mechanistic concepts comparable to that in the companion volume, Part A, Structures and Mechanisms. Together, the two volumes are intended to provide the advanced undergraduate or beginning graduate student in chemistry with a sufficient foundation to comprehend and use the research literature in organic chemistry.

Mass Spectrometry: Principles and Applications 3rd edition

Mass Spectrometry: Principles and Applications 3rd edition
Mass Spectrometry


Wiley-Interscience | ISBN:0470033118 | Edition - 2007-11-16 | PDF | 502 pages | 4.8 MB | Rapidshare & Megaupload

The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra.

This new edition has been thoroughly revised and updated and has been redesigned to give the book a more contemporary look. As with previous editions it contains numerous examples, references and a series of exercises of increasing difficulty to encourage student understanding. Updates include: Increased coverage of MALDI and ESI, more detailed description of time of flight spectrometers, new material on isotope ratio mass spectrometry, and an expanded range of applications.

Mass Spectrometry, Third Edition is an invaluable resource for all undergraduate and postgraduate students using this technique in departments of chemistry, biochemistry, medicine, pharmacology, agriculture, material science and food science. It is also of interest for researchers looking for an overview of the latest techniques and developments.




Ebooks Collection:
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A Guidebook to Mechanism in Organic Chemistry (6th Edition)

A Guidebook to Mechanism in Organic Chemistry (6th Edition)


Prentice Hall | 416 | 1996-02-19 | 0582446953 | PDF | 6.5 Mb

The book is a condensed source of information of various different subjects relating to organic chemistry. In saying so it is a general overview of practical organic chemistry. Sykes is clear in his explanation and elucidation on various reaction mechanisms and as he states early on, he does promote a mechanistic perspective of organic chemistry.

Sykes is particularly useful for individuals who have done introductory organic chemistry and are venturing into deeper topics of the subject, i.e. stereochemistry and synthesis as examples (a lot of universities offer courses which purely concentrate on these regions of study).

Now the greatest downfall I see about the text is the price. March's advanced organic chemistry is much more extensive, newer and my personal opinion is that the authorship is better in March's

Another downfall is the age, although a lot of the topics that have been introduced in this book have not changed significantly and therefore dont seriously affect the text's validity; I still feel it should have had an update. This book was published in the 1980's (the late era of the decade).

All I am saying is that Syke's book is a classic, one can learn a lot from it and it is a fairly good reference book, however to my understanding there are better texts of the same genre covering practically the same themes as in this book.

I would strongly recommend any individual interested in this book to have a look at March's Advanced Organic Chemistry.

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Principles of Food Chemistry, 3rd Edition (Food Science Texts Series)

Principles of Food Chemistry, 3rd Edition (Food Science Texts Series)


John M.de Man | Springer | 520 | 1999-02-01 | ISBN:083421234X | 9780834212343 | pdf | 19624 KB


Book Description:

This popular and widely used text/reference has been updated, revised and substantially expanded.
The new edition contains a complete overview of the chemical and physical properties of the major and minor food components and their changes during processing, handling and storage. Food chapters cover water, lipids, carbohydrates, protein, minerals, vitamins and enzymes. Also covered are color, flavor and texture, as well as additives and contaminants. A new chapter discusses the bases of regulatory control of food composition and quality. Full of illustrations and tables, each chapter also contains a bibliography, providing readers with quick access to the relevant literature. An Instructor's manual is available to adopting professors.

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T. W. Swaddle , "Inorganic Chemistry: An Industrial and Environmental Perspective"

T. W. Swaddle , "Inorganic Chemistry: An Industrial and Environmental Perspective"

T. W. Swaddle , "Inorganic Chemistry: An Industrial and Environmental Perspective"
Academic Press; 1 edition (February 24, 1997) | ISBN: 0126785503 | 482 pages | PDF | 21,7 Mb

This book addresses the question, What is inorganic chemistry good for? rather than the more traditional question, How can we develop a theoretical basis for inorganic chemistry from sophisticated theories of bonding? The book prepares students of science or engineering for entry into the multi-billion-dollar inorganic chemical and related industries, and for rational approaches to environmental problems such as pollution abatement, corrosion control, and water treatment. A much expanded and updated revision of the 1990 text, Applied Inorganic Chemistry (University of Calgary Press), Inorganic Chemistry covers topics including atmospheric pollution and its abatement, water conditioning, fertilizers, cement chemistry, extractive metallurgy, metallic corrosion, catalysts, fuel cells and advanced batter technology, pulp and paper production, explosives, supercritical fluids, sol-gel science, materials for electronics, and superconductors. Though the book waswritten as a textbook for undergraduates with a background of freshman chemistry, it will also be a valuable sourcebook for practicing chemists, engineers, environmental scientists, geologists, and educators.

Key Features
* Presents the principles of inorganic chemistry in terms of its relevance to the real world of industry and environmental protection
* Serves as a concise reference for practicing scientists, engineers, and educators
* Emphasizes industrially relevant energetics and kinetics rather than bonding theories
* Features extensive cross-referencing for easy location of supporting material


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Transformers[2007]DvDrip[Eng]-aXXo

Transformers[2007]DvDrip[Eng]-aXXo



1 - http://megafilegarden.com/download.php?id=kWr6SRKLRGu
2 - http://megafilegarden.com/download.php?id=ZuJlGkFrVht
3 - http://megafilegarden.com/download.php?id=nH1QRBUi1At
4 - http://megafilegarden.com/download.php?id=fpHz1zMKEiq
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BATMAN - THE ANIMATED SERIES (1992): VOLUMES 1-4

BATMAN - THE ANIMATED SERIES (1992): VOLUMES 1-4 [ORIGINAL UNCUT DVD]
Megaupload Batman TAS links are of the original uncut DVD i.e. 175MB each



VOLUME 1
Disc One

On Leather Wings- http://rapidshare.com/files/12200564/BTAS101.avi.001 http://rapidshare.com/files/12201081/BTAS101.avi.002
Christmas With The Joker- http://www.megaupload.com/?d=2I3LACOM
Nothing to Fear- http://www.megaupload.com/?d=NCNW54FP
The Last Laugh- http://www.megaupload.com/?d=NO1ZVX9S
Pretty Poison- http://www.megaupload.com/?d=W04L8YTN
The Underdwellers- http://www.megaupload.com/?d=1S12FMEG
P.O.V.- http://www.megaupload.com/?d=NHD9EFTN

Disc Two

The Forgotten- http://www.megaupload.com/?d=JYT18VTU
Be a Clown- http://www.megaupload.com/?d=TO639I6K
Two Face: Part One- http://www.megaupload.com/?d=Z6WATNF3
Two Face: Part Two- http://www.megaupload.com/?d=NNQP3KTB
It's Never Too Late- http://www.megaupload.com/?d=V0CERDB3
I've Got Batman in my Basement- http://www.megaupload.com/?d=HJI2LOUE
Heart of Ice- http://www.megaupload.com/?d=OHV6SJMS

Disc Three

The Cat and the Claw: Part One- http://www.megaupload.com/?d=MQFXXZYN
The Cat and the Claw: Part Two- http://www.megaupload.com/?d=QHA3V70S
See No Evil- http://www.megaupload.com/?d=MI5DHRX6 (http://rapidshare.com/files/12202585/BTAS117.avi.001 http://rapidshare.com/files/12202565/BTAS117.avi.002)
Beware the Gray Ghost- http://www.megaupload.com/?d=RENTI48E
Prophecy of Doom- http://www.megaupload.com/?d=TI6N25KU
Feat of Clay: Part One- http://www.megaupload.com/?d=30CSP6BM
Feat of Clay: Part Two- http://www.megaupload.com/?d=WE8R4JVS

Disc Four

The Joker's Favor- http://www.megaupload.com/?d=SOLER6Q7 (http://rapidshare.com/files/12202593/BTAS122.avi.001 http://rapidshare.com/files/12202576/BTAS122.avi.002)
Vendetta- http://www.megaupload.com/?d=KHFJO8V7 (http://rapidshare.com/files/12202599/BTAS123.avi.001 http://rapidshare.com/files/12202578/BTAS123.avi.002)
Fear of Victory- http://www.megaupload.com/?d=E9L3KCG8 (http://rapidshare.com/files/12202597/BTAS124.avi.001 http://rapidshare.com/files/12202579/BTAS124.avi.002)
The Clock King- http://www.megaupload.com/?d=RZWZK774 (http://rapidshare.com/files/12202758/BTAS125.avi.001 http://rapidshare.com/files/12202747/BTAS125.avi.002)
Appointment in Crime Alley- http://www.megaupload.com/?d=TAAZKGC1 (http://rapidshare.com/files/12202759/BTAS126.avi.001 http://rapidshare.com/files/12202744/BTAS126.avi.002)
Mad as a Hatter- http://www.megaupload.com/?d=7U1PQGYQ
Dreams in Darkness- http://www.megaupload.com/?d=QBV7T71A (http://rapidshare.com/files/12202765/BTAS128.avi.001
http://rapidshare.com/files/12202746/BTAS128.avi.002)

DVD Extras

Dark Knight’s First Night - The test pilot Bruce and Eric pitched to the networks- http://www.megaupload.com/?d=1VB6XG7X
The Legacy Continues - A retrospect on Batman. Included words from Timm, Dini, Radomski, Hamill, Conroy and a few others in the comic biz- http://www.megaupload.com/?d=CKSVPDOI




VOLUME 2

Disc One

Eternal Youth- http://www.megaupload.com/?d=D11LT149
Perchance to Dream- http://www.megaupload.com/?d=AANMBXKT
The Cape and Cowl Conspiracy- http://www.megaupload.com/?d=OCWAGFWB
Robin's Reckoning Part One- http://www.megaupload.com/?d=HHKLE0QI
Robin's Reckoning Part Two- http://www.megaupload.com/?d=21NWMR4F
The Laughing Fish- http://rapidshare.com/files/12306523/BTAS234.avi.001 http://rapidshare.com/files/12306369/BTAS234.avi.002
Night of the Ninja- http://www.megaupload.com/?d=SEQETRWN

Disc Two

Cat Scratch Fever- http://www.megaupload.com/?d=1JJ5OVW8
The Strange Secret of Bruce Wayne- http://www.megaupload.com/?d=AA5B0T3V
Heart of Steel Part One- http://www.megaupload.com/?d=C65FYWRT
Heart of Steel Part Two- http://www.megaupload.com/?d=DAA00KMY
If You're So Smart, Why Aren't You Rich?- http://www.megaupload.com/?d=9VY4BY1O
Joker's Wild- http://www.megaupload.com/?d=2M2SR91Q
Tyger, Tyger- http://www.megaupload.com/?d=1WSIROWG

Disc Three

Moon of the Wolf- http://www.megaupload.com/?d=P91606AX
Day of the Samurai- http://www.megaupload.com/?d=EZ4B3AO0
Terror in the Sky- http://www.megaupload.com/?d=L4GQ54X8
Almost Got 'Im- http://www.megaupload.com/?d=K73INCPG
Birds of a Feather- http://www.megaupload.com/?d=IOHWJ5Q6
What is Reality?- http://www.megaupload.com/?d=KUEGO9IR
I am the Night- http://www.megaupload.com/?d=PYPAQDP6

Disc Four

Off Balance- http://www.megaupload.com/?d=NF1J69PC
The Man Who Killed Batman- http://www.megaupload.com/?d=TTR9C68A
Mudslide- http://www.megaupload.com/?d=OH3PM3LK
Paging the Crime Doctor- http://www.megaupload.com/?d=GACR46C3
Zatanna- http://www.megaupload.com/?d=T5UPJ1JM
The Mechanic- http://www.megaupload.com/?d=O9ACWYBD
Harley and Ivy- http://www.megaupload.com/?d=IL2RHE1C

Bonus Features

Robin’s Rising- http://www.megaupload.com/?d=XPOL2TAE
Robin’s Reckoning Pt 1 Audio Commentary- http://www.megaupload.com/?d=H6ZLMTYW
Heart of Steel Pt 2 Audio Commentary- http://www.megaupload.com/?d=Z8UFZXD9
Almost Got Im Audio Commentary- http://www.megaupload.com/?d=JATQVI5L
Voices of the Knight - A look that the voice actors on the show- http://www.megaupload.com/?d=XZOGPE2D
Harley & Ivy Audio Commentary- http://www.megaupload.com/?d=85TSPPCU



VOLUME 3

Disc One

Shadow of the Bat Part 1- http://www.megaupload.com/?d=Z46TBXIG
Shadow of the Bat Part 2- http://www.megaupload.com/?d=506S6DEW
Blind as a Bat- http://www.megaupload.com/?d=I4S2SI4C
The Demon's Quest Part 1- http://www.megaupload.com/?d=GUMUWAFF
The Demon's Quest Part 2- http://www.megaupload.com/?d=EI7H2G7T
His Silicon Soul- http://www.megaupload.com/?d=RXPDQNUU
Fire From Olympus- http://www.megaupload.com/?d=QDXY3MF1

Disc Two

Read My Lips- http://www.megaupload.com/?d=BNVXGUL4
The Worry Men- http://www.megaupload.com/?d=0WBONLOQ
Sideshow- http://www.megaupload.com/?d=M4OUNP5A
A Bullet for Bullock- http://www.megaupload.com/?d=E0G6GPL6
Trial- http://www.megaupload.com/?d=WGE3XQWT
Avatar- http://www.megaupload.com/?d=J38FVL8I
House and Garden- http://www.megaupload.com/?d=DX6CEX33

Disc Three

The Terrible Trio- http://www.megaupload.com/?d=OE6CYR4R
Harlequinade- http://www.megaupload.com/?d=MOETDLDC
Time Out of Joint- http://www.megaupload.com/?d=2DQ16PNT
Catwalk- http://www.megaupload.com/?d=YYPF2485
Bane- http://www.megaupload.com/?d=TX7JJEQS
Baby-Doll- http://www.megaupload.com/?d=3Z3234TX
The Lion and The Unicorn- http://www.megaupload.com/?d=ZPUEE28H

Disc Four

Showdown- http://www.megaupload.com/?d=9ZDRWEWL
Riddler's Reform- http://www.megaupload.com/?d=UZUB69A3
Second Chance- http://www.megaupload.com/?d=Q0QQC35V
Harley's Holiday- http://www.megaupload.com/?d=4IP0PWJI
Lock-Up- http://www.megaupload.com/?d=IZE7IF5G
Make 'Em Laugh- http://www.megaupload.com/?d=GJAOPBG9
Deep Freeze- http://www.megaupload.com/?d=8FXJI3Q2
Batgirl Returns- http://www.megaupload.com/?d=ACIBXIDY

Bonus Features

Gotham's New Knight - A Look at the Batgirl Character- http://www.megaupload.com/?d=JKWU3FMD
Read My Lips Audio Commentary- http://www.megaupload.com/?d=A3GW766W
House and Garden Video Commentary- http://www.megaupload.com/?d=WLMA308P
Harlenquinade Audio Commentary- http://www.megaupload.com/?d=B246QJSD




VOLUME 4: THE NEW BATMAN ADVENTURES

Disc One

Holiday Knights- http://www.megaupload.com/?d=Y8XN9DRV
Sins of the Father- http://www.megaupload.com/?d=YGFJ9C1G
Cold Comfort- http://www.megaupload.com/?d=TWD2JW2J
You Scratch My Back- http://www.megaupload.com/?d=RO1MDN8Q
Double Talk- http://www.megaupload.com/?d=FAG3OBC3
Never Fear- http://www.megaupload.com/?d=3UMTCPNH

Disc Two

Joker’s Millions- http://www.megaupload.com/?d=IKNHUDCX
Growing Pains- http://www.megaupload.com/?d=XP27ZLB7
Love is a Croc- http://www.megaupload.com/?d=5CM52O61
Torch Song- http://www.megaupload.com/?d=HQVLXYLY
The Ultimate Thrill- http://www.megaupload.com/?d=Y1P0R22L
Over the Edge- http://www.megaupload.com/?d=F91QB5V2

Disc Three

Mean Seasons- http://www.megaupload.com/?d=4M7N5XXD
Critters- http://www.megaupload.com/?d=8TNW0MYF
Cult of the Cat- http://www.megaupload.com/?d=VC62TOBF
Animal Act- http://www.megaupload.com/?d=GZC968IK
Old Wounds- http://www.megaupload.com/?d=1701F0TQ
The Demon Within- http://www.megaupload.com/?d=2NPG3MLC

Disc Four

Legends of the Dark Knight- http://www.megaupload.com/?d=KRWKN1V3
Girls' Nite Out- http://www.megaupload.com/?d=Q4JXPFM4
Mad Love- http://www.megaupload.com/?d=6Z577E3X
Chemistry- http://www.megaupload.com/?d=5DFQ84SV
Beware the Creeper- http://www.megaupload.com/?d=DLONQWDE
Judgment Day- http://www.megaupload.com/?d=R7RR3FSD

Bonus Features

Arkham's Finest: Inside Batman's Rogue Gallery- http://www.megaupload.com/?d=MQWS21D3
Mr Freeze- http://www.megaupload.com/?d=7M71G4XK
Ras Al Ghul- http://www.megaupload.com/?d=MXTUDIMO
The Riddler- http://www.megaupload.com/?d=DPDJ3TFZ
Harley Quinn- http://www.megaupload.com/?d=11HMYC97
Penguin- http://www.megaupload.com/?d=NDRM2WUO
Joker- http://www.megaupload.com/?d=9K86XI4M
Scarecrow- http://www.megaupload.com/?d=3N9KJV0J
Two-Face- http://www.megaupload.com/?d=5EXEQQ2H
Poison Ivy- http://www.megaupload.com/?d=H7PKCPTK
Over the Edge Audio Commentary- http://www.megaupload.com/?d=THP6TOZS
Critters Audio Commentary- http://www.megaupload.com/?d=1ETENZN5
Legends of the Dark Knight Audio Commentary- http://www.megaupload.com/?d=WEN97CJ5



VOLUME 4: THE NEW BATMAN ADVENTURES (Mirror Links - Uncut Version)

The New Batman Adventures was the successor to the highly acclaimed American animated television series Batman: The Animated Series. There has been some debate over the official title of this show (some refer to it as "Batman: Gotham Knights"), but creator Bruce Timm has clarified on numerous occasions that The New Batman Adventures is the official title. The DVD release of this show is known as "Batman: The Animated Series Volume 4 (from The New Batman Adventures)"

The New Batman Adventures (Batman Gotham Knights):
Episode 01 Holiday Knights
Episode 02 Sins of the Father
Episode 03 Cold Comfort
Episode 04 Double Talk
Episode 05 You Scratch My Back
Episode 06 Never Fear
Episode 07 Joker's Millions
Episode 08 Growing Pains
Episode 09 Love is a Croc
Episode 10 Torch Song
Episode 11 The Ultimate Thrill
Episode 12 Over the Edge
Episode 13 Mean Seasons
Episode 14 Critters
Episode 15 Cult of the Cat
Episode 16 Animal Act
Episode 17 Old Wounds
Episode 18 The Demon Within
Episode 19 Legends of the Dark Knight
Episode 20 Girl's Nite Out
Episode 21 Mad Love
Episode 22 Chemistry
Episode 23 Beware the Creeper
Episode 24 Judgment Day

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http://rapidshare.com/files/12345809/TNBA14.avi.001
http://rapidshare.com/files/12345824/TNBA14.avi.002
http://rapidshare.com/files/12346082/TNBA15.avi.001
http://rapidshare.com/files/12346065/TNBA15.avi.002
http://rapidshare.com/files/12346097/TNBA16.avi.001
http://rapidshare.com/files/12346066/TNBA16.avi.002
http://rapidshare.com/files/12346113/TNBA17.avi.001
http://rapidshare.com/files/12346093/TNBA17.avi.002
http://rapidshare.com/files/12346087/TNBA18.avi.001
http://rapidshare.com/files/12346067/TNBA18.avi.002
http://rapidshare.com/files/12346109/TNBA19.avi.001
http://rapidshare.com/files/12346111/TNBA19.avi.002
http://rapidshare.com/files/12346089/TNBA20.avi.001
http://rapidshare.com/files/12346074/TNBA20.avi.002
http://rapidshare.com/files/12346092/TNBA21.avi.001
http://rapidshare.com/files/12346073/TNBA21.avi.002
http://rapidshare.com/files/12346134/TNBA22.avi.001
http://rapidshare.com/files/12346084/TNBA22.avi.002
http://rapidshare.com/files/12346106/TNBA23.avi.001
http://rapidshare.com/files/12346078/TNBA23.avi.002
http://rapidshare.com/files/12346107/TNBA24.avi.001
http://rapidshare.com/files/12346079/TNBA24.avi.002